Guatemala: List of the 25 Largest Cities by Population

Antigua, Guatemala: Best Things to Do - Top Picks

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1. Guatemala City – 1,221,739 Known as the capital and largest city, it’s the political, economic, and cultural heart of Guatemala.
2. Mixco – 465,773 A city adjacent to Guatemala City, part of the metropolitan area, known for its residential communities.
3. Villa Nueva – 433,734 Located just south of Guatemala City, it’s an industrial hub with a growing population.
4. San Juan Sacatepéquez – 218,156 Known for its agricultural activities and proximity to Guatemala City.
5. Cobán – 212,047 The capital of Alta Verapaz, known for its coffee production and natural beauty.
6. Quetzaltenango – 180,706 The second-largest city, known for its colonial architecture and as a cultural center.
7. Jalapa – 159,840 Located in the southeastern part of the country, known for its agricultural production.
8. Escuintla – 156,313 A coastal city on the Pacific, known for its port and industrial activities.
9. Villa Canales – 155,422 A municipality near Guatemala City, known for its residential areas.
10. Jutiapa – 145,880 Located in the southeastern region, known for its agricultural activities.
11. San Miguel Petapa – 129,124 A municipality close to Guatemala City, known for its residential communities.
12. Huehuetenango – 117,818 A city in the western highlands, known for its coffee production and indigenous culture.
13. Chiquimula – 111,505 Located in the eastern part of the country, known for its agricultural activities.
14. Coatepeque – 105,415 A city near Lake Coatepeque, known for its tourism and natural beauty.
15. Chinautla – 104,972 A municipality close to Guatemala City, known for its residential areas.
16. Retalhuleu – 98,003 A city known for its agricultural production and the nearby Xetulul theme park.
17. Santa Catarina Pinula – 96,903 A suburban municipality near Guatemala City, known for its residential areas.
18. Amatitlán – 88,064 Located near Lake Amatitlán, it’s known for its tourism and natural scenery.
19. Sololá – 88,023 The capital of Sololá Department, known for its indigenous culture and scenic views of Lake Atitlán.
20. Sanarate – 85,545 A city in the El Progreso Department, known for its agricultural industry.
21. Chimaltenango – 82,004 A city located between Guatemala City and Antigua, known for its agriculture.
22. La Antigua Guatemala – 53,210 A UNESCO World Heritage site, known for its colonial architecture and cultural significance.
23. Guastatoya – 50,934 A city in the El Progreso Department, known for its agriculture and historical importance.
24. Santa Lucia Cotzumalguapa – 50,387 A city in the Escuintla Department, known for its ancient Mayan ruins.
25. San Pedro Ayampuc – 47,284 A municipality close to Guatemala City, known for its rural charm and proximity to the capital.

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