1. Santiago – 6,900,000
Capital and largest city, surrounded by the Andes.
2. Puente Alto – 670,000
Largest commune within Greater Santiago.
3. Antofagasta – 430,000
Northern port city and mining center.
4. Viña del Mar – 330,000
Beach resort city with gardens and festivals.
5. Valparaíso – 300,000
Colorful port city with steep funiculars.
6. Talcahuano – 280,000
Industrial port city in the south.
7. San Bernardo – 270,000
Suburb in the Santiago metropolitan area.
8. Temuco – 260,000
Cultural gateway to the Araucanía region.
9. Iquique – 250,000
Coastal desert city known for duty-free zone.
10. Concepción – 220,000
Major university and industrial city.
11. La Serena – 220,000
Colonial city with beaches and observatories.
12. Rancagua – 210,000
Mining and agricultural city south of Santiago.
13. Arica – 200,000
Northernmost city with warm beaches.
14. Talca – 200,000
Agricultural hub in central Chile.
15. Chillán – 190,000
City with hot springs and skiing nearby.
16. Los Ángeles – 190,000
Forest and agriculture-based economy.
17. Calama – 160,000
Mining town near the Atacama Desert.
18. Copiapó – 160,000
Mining city in the Atacama region.
19. Osorno – 150,000
Dairy and livestock capital in southern Chile.
20. Valdivia – 150,000
River city with German heritage.
21. Punta Arenas – 130,000
Southernmost continental city in Chile.
22. Quilpué – 130,000
Residential city in the Valparaíso region.
23. Curicó – 120,000
Known for wine production.
24. Coronel – 120,000
Former coal-mining town south of Concepción.
25. San Antonio – 110,000
Important commercial seaport near Santiago.