1. Guayaquil – 3,200,000
Ecuador’s largest city and main Pacific port.
2. Quito – 2,700,000
High-altitude capital with colonial old town.
3. Cuenca – 700,000
UNESCO-listed city known for architecture and expat community.
4. Santo Domingo – 460,000
Commercial hub linking the coast and highlands.
5. Machala – 350,000
Banana-exporting center near the Gulf of Guayaquil.
6. Durán – 300,000
Suburban city across the river from Guayaquil.
7. Manta – 280,000
Important coastal port and beach destination.
8. Portoviejo – 270,000
Capital of Manabí with agricultural importance.
9. Loja – 250,000
Southern city known for music and culture.
10. Ambato – 250,000
City of flowers and fruit in the central Andes.
11. Esmeraldas – 230,000
Northern coastal city with Afro-Ecuadorian culture.
12. Quevedo – 220,000
Agricultural center in Los Ríos province.
13. Riobamba – 210,000
Highland city near Chimborazo volcano.
14. Milagro – 200,000
Sugarcane-growing city near Guayaquil.
15. Ibarra – 180,000
Highland city north of Quito with colonial charm.
16. Latacunga – 180,000
Gateway to Cotopaxi volcano.
17. Babahoyo – 170,000
Rice and banana center in coastal lowlands.
18. Tulcán – 150,000
Northern border city near Colombia.
19. Santa Elena – 140,000
Coastal city and capital of the Santa Elena Province.
20. Nueva Loja (Lago Agrio) – 120,000
Oil industry hub in the Amazon region.
21. Puyo – 110,000
Amazon gateway in Pastaza province.
22. Tena – 100,000
Adventure tourism and rainforest city.
23. Macas – 50,000
Small city on the edge of the Amazon.
24. Zamora – 40,000
City known for biodiversity and mining.
25. Azogues – 35,000
Capital of Cañar with colonial churches.
