1. Asunción – 530,000
The capital and largest city of Paraguay, located on the Paraguay River.

2. Ciudad del Este – 320,000
Border city known for trade and proximity to Iguazu Falls.

3. San Lorenzo – 250,000
Major suburb of Asunción and university hub.

4. Luque – 250,000
Suburban city, home to Paraguay’s main airport.

5. Capiatá – 230,000
Rapidly growing city in the Asunción metro area.

6. Lambaré – 170,000
Residential city near central Asunción.

7. Fernando de la Mora – 170,000
Urban city part of the Greater Asunción area.

8. Limpio – 140,000
Historic city known for its churches.

9. Ñemby – 130,000
Southern suburb with growing infrastructure.

10. Encarnación – 130,000
Southern city known for Jesuit ruins and beaches.

11. Mariano Roque Alonso – 100,000
City known for Paraguay’s largest expo center.

12. Itauguá – 100,000
Town known for traditional lace making.

13. Pedro Juan Caballero – 100,000
Border city with strong commerce ties to Brazil.

14. Villa Elisa – 95,000
Industrial suburb south of Asunción.

15. Caaguazú – 80,000
Commercial city in central Paraguay.

16. Concepción – 80,000
Northern port city with historical relevance.

17. Coronel Oviedo – 75,000
Strategically located city at a national crossroads.

18. Caacupé – 70,000
Religious pilgrimage site with a famous basilica.

19. Villarrica – 65,000
Cultural and educational center.

20. San Antonio – 60,000
Port and suburban city.

21. Horqueta – 55,000
Agricultural town in northern Paraguay.

22. Ypané – 50,000
Town with colonial heritage and industry.

23. Paraguarí – 35,000
Historic city in the hills of southern Paraguay.

24. San Estanislao – 35,000
University town in northeastern Paraguay.

25. Ayolas – 30,000
City near the Yacyretá Dam on the Paraná River.