Sao Tome and Principe: List of the Largest Cities by Population

A pristine Sao Tome and Principe beach on a sun-drenched day. Turquoise waters gently lapping against a golden sand shore, framed by lush, verdant palm trees swaying in the breeze. In the distance, dramatic volcanic peaks rise up, their rugged profiles silhouetted against a brilliant azure sky. Warm, diffused lighting filters through wispy clouds, casting a soft, natural glow over the tranquil scene. A serene, idyllic paradise, perfect for travelers seeking to soak up the natural beauty and relaxed atmosphere of this enchanting island nation.
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Hotels by Trip.com

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1. São Tomé – 71,000
Capital and largest city; main port, political center, and cultural hub.


2. Santo António – 8,000
Capital of Príncipe Island, known for colonial architecture and fishing.


3. Neves – 8,000
Port town on the northwest coast of São Tomé Island, known for fishing and trade.


4. Santana – 7,000
Coastal town on São Tomé Island with fishing and cocoa farming.


5. Trindade – 7,000
Inland town near São Tomé, known for agriculture and local commerce.


6. Guadalupe – 7,000
Town in the north of São Tomé Island, known for cocoa plantations.


7. Santa Cruz – 3,000
Small coastal village with fishing and subsistence farming.


8. Pantufo – 3,000
Seaside settlement just south of São Tomé city.

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